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Considering the energy changes associated with the individual reactions below, which reaction can be coupled with...


Considering the energy changes associated with the individual reactions below, which reaction can be coupled with the hydroly
A) Succinate + HSCOA + HPO42-→ succinyl CoA + H20 B) Fructose 6-phosphate + HPO42- → fructose 1,6-bisphosphate + H2O C) 3-pho
Considering the energy changes associated with the individual reactions below, which reaction can be coupled with the hydrolysis of ATP to generate a coupled reaction that is energetically favorable? Energy. change -7.3 kcal/mol ATP + H20 → ADP + HPO42- succinyl CoA + H20 → succinate + HSCOA + -9.4 HPO42- fructose 1,6-bisphosphate + H20 → fructose 6- kcal/mol -3.9 kcal/mol phosphate + HPO42- 1,3-bisphosphoglycerate + H2O → 3- phosphoglycerate + HPO42- -11.8 kcal/mol
A) Succinate + HSCOA + HPO42-→ succinyl CoA + H20 B) Fructose 6-phosphate + HPO42- → fructose 1,6-bisphosphate + H2O C) 3-phosphoglycerate + HPO42-→ 1,3-bisphosphoglycerate + H20 All of the reactions can be coupled with the hydrolysis of ATP to generate a D) coupled reaction that is energetically favorable.
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Answer #1

For energetically favour reaction energy change on coupling should be negative .

A ) reversing reaction ( 2 ) and adding with first reaction

Energy change = —7.3 + 9.4 = 2.1 Kcal / mol ( unfavourable )

B )reversing reaction ( 3) and adding with first reaction

Energy change = —7.3 + 3.9 = — 3.4 Kcal / mol (favourable  )

C ) reversing reaction ( 4) and adding with first reaction

Energy change = —7.3 + 11.8 = 4.5 Kcal / mol ( unfavourable )

So correct answer is option ( B )

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