Question

(TRUE OR FALSE)

please make sure to answer all parts as they're related.

part 1

Cooperative) This information is correct as indicated by the 'Cooperative' segment of the web text: The two conformations of hemoglobin are indistinguishable Choose... Oxygen binding 'strains' the hemoglobin structure Changes in each subunit (monomer) physically influence the state(s) of others The words steric, cooperative, sigmoidal and hyperbolic are each directly linked from the text so you can learn more Choose... Choose... v Choose... \

part 2

part 3

Answer 1

The two conformations of haemoglobin are indistinguishable- false

The oxyhemoglobin has significantly lower absorption of the 660 nm wavelength than deoxyhemoglobin, while at 940 nm its absorption is slightly higher.

Oxygen binding strains the haemoglobin structure- true

As haemoglobin turns into the Tensed state from a relaxed state.

Changes in each subunit physically influence the staate of others-true

Binding of oxygen by one subunit influences the binding in other subunits also.

In sickle cell anaemia hemoglobin tetramers stick together forming long chains.-True

hemoglobin tetramers stick to each other, forming long fibers (i.e., polymerizing) instead of remaining independent

Amount of hemoglobin that has an attached glucose molecule is an indicator of sugar levels in the blood- true

When blood glucose levels are high, glucose molecules attach to the hemoglobin in red bloodcells. The longer hyperglycemia occurs in blood, the more glucose binds to hemoglobin in the red bloodcells and the higher the glycated hemoglobin. Once a hemoglobin molecule is glycated, it remains that way.

co poisoning acts by ALTERING hemoglobin's ability to carry oxygen- true

False- Half life of red blood cells is 60 days.