Question

When performing a Friedel-Crafts alkylation reaction, not only does one have the problems of multiple alkylation and rearrangement of the cation, but the presence of strong electron donating groups(yes, donating is correct) prevents reaction. Provide an explanation for this. Metallocenes, like ferrocene cannot be nitrated. Why? Draw the structure of the diacetylferrocene you would obtain if ferrocene were diacetylated. Draw an arrow pushing mechanism for the formation of the acylium ion when acetic anhydride reacts with phosphoric acid. Provide the major organic product(s) for the following reactions. 5. H2SO4

Answer 1

Page No.: - Date: 11 | In Friedel Graft reaction, we duse Allty as a catalyst which is a să lewis base lie it has a strong tendency to accept electrons. And stan presence of strong electron donating group will create an interaction between electron donating an group and B. That means strong electron donating I group will interact with Alch rather than activating the benzene ring and this will cause a positive charge next to benzene ding which deactivates the benzene ring and friedel Craft reaction will not occur. @ | fa Fennocene can not be nitrated using Hng: 4.50, system Because HNO is a Oxidizing agent and it will oxidize fert into | fear rather than atloching to Cyclopentadienyt ring and will form | fennocinium ion which is highly unstable. Conc. Hnos fe 1 Fem faceto OSO Diacetyl fermocene

Page No.: Date: 17 ou o Ton - HC- Acetic acid Acyliomion Autiomien H-HSO, COCA-CM 4 ATO Theme thing as QL-deactivating group that's matuck will oan. Josu