Question

39. Signal transduction pathways that require the synthesis of new considered fast pathways proteins are generally A. True B. False 40. A synthesized protein with the following configuration will have its N-terminus and C-terminus in which configuration? Signal- protein -stop- protein A. N-terminus ER, C-terminus->Cytoplasm B. N-terminus- Cytoplasm, C-terminus- ER C. N-terminus- ER, C-terminus ER D. N-terminus Cytoplasm, C-terminus Cytoplasm 41. A scientist has just designed a new drug to treat cancer. She realises that it takes onl She correctly concludes that the drug acts by ly a few mins for the drug to take effect after binding to its receptor on the cell surface. A. Inhibiting/affecting already synthesized proteins via post-translational modifications B. Increasing DNA activity C. Modifying ribosomal activation D. Reversing the harmful mutagenesis effects that happened to the cell

Answer 1

39. False Signalling pathways that require synthesis of new proteins are slow as compared to pathways that involves post-translational modification of proteins.

40. A. newly synthesised proteins have a N-terminal signal peptide, that directs it to the endoplasmic reticulum. The N-terminal enters the ER lumen as the protein is still being synthesised.

41. A. drugs that acts through second messengers and post-translationally modifies proteins acts in a short time duration (usually minutes).