How is bonding a factor ion creating the effects that drugs produce?
How is bonding a factor ion creating the effects that drugs produce?
Homework Answers
Answer:
Bonding factors:
a. Chemical factor: different chemical composition used to improve the stability and systematic availability of drug eg: esters are prepared by acids and bases to produces more stable drugs.
b. Salts of weak bases, it lower pH of diffusion layer and absorption of basic drugs and more effective
3. ionisation sate of drug: effective drugs has pka and pH of the fluids at the absorption site is determined by Henderson-hesselbatch equation
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