1. Explain chemiosmotic coupling and its relation to oxidative phosphorylation:
2.Illustrate and describe the mechanism of ATP synthase conversion of gradient energy to mechanical energy to chemical energy.
3. Explain common sense feedback regulation of metabolic pathways.
1. Explain chemiosmotic coupling and its relation to oxidative phosphorylation: 2.Illustrate and describe the mechanism of...
Oxidative phosphorylation is achieved through chemiosmotic coupling, which turns chemical energy into osmotic potential energy that is used to synthesize the energy “currency” of the cell (ATP). This process is divided into stage 1 (electron transport chain) and stage 2 (ATP synthase). Answer the following questions about each stage: In stage 1, what is the energy source used to form the proton gradient across the inner membrane and what is the principal carrier of this energy source? In stage 2,...
Explain the chemiosmotic mechanism of ATP generation. How does oxidative phosphorylation compare with substrate level phosphorylation found in glycolysis and the Kreb’s cycle?
Explain the chemiosmotic mechanism of ATP generation. How does oxidative phosphorylation compare with substrate level phosphorylation found in glycolysis and th e Kreb’s cycle?
What is substrate level and respiration-linked phosphorylation, • What is oxidative phosphorylation, how is it different from photophosphorylation. • What is the chemiosmotic theory • describe the electron transport chain (ETC) with different complexes and components, what are the electron carries, what forms are electron moved etc. • explain the Q cycle • Describe the different cytochromes and iron-sulfur proteins of the ETC • What is proton motive force, chemical potential and electrical potential • describe the structure of ATP...
QUESTION 2 What is the main mechanism of action for oxidative phosphorylation? A Uses the free energy of the proton gradient generated as a result of transferring electrons from NADH OF FADH2 to O2 by a series of electron carriers for ATP production B. Uses the net yield of ATP produced by Glycolysis and the Citric Acid Cycle to produce more ATP. Uses the free energy released during redox reactions in Complexes I-IV (the electron transport chain) and is uncoupled...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
1.What does an uncoupler do? 2.Cyanide is a potent poison and can cause rapid death in humans. Explain its mechanism! 3.Explain the coupling between the electron transport chain and oxidative phosphorylation. Include a description of the mechanism of ATP synthase PLEASE ANSWER ALL QUESTIONS
1. Show 4 metabolic reactions catalyzed by phosphatases and describe their role in metabolism and also describe the regulation of each of these enzymes. You must include at least two different metabolic pathways. 2. a. The statin drugs are prescribed for people with high cholesterol levels. Describe their mechanism of action including a kinetic analysis. b. What are the differences/similarities between the various statin drugs and the natural substrate? c. Like the statins, many drugs act as inhibitors of metabolic pathways. Choose another drug that inhibits...
13. Describe 2 mechanisms whereby ATP is generated during cellular respiration Mechanism 1: Mechanism 2: 14. Indicate the MAIN molecules that enter and exit each of these processes? Molecule(s) IN Process Molecule(s) OUT Glycolysis Pyruvate Oxidation Citric Acid/Krebs Cycle ETC Photophosphorylation Calvin Cycle 15. Isocitrate is a 6 carbon molecule that is oxidized to a-ketoglutarate (a 5 carbon molecule) by the enzyme isocitrate dehydrogenase. What happens to the extra carbon atom in this reaction and in which process (listed in...
Chapter 7 1. What is the main source of energy for most living organisms? 2. What are the laws that gover the life and death of cells called? 3. Why is an organism's ability to exchange energy with its environment referred to as an open system? 4. What is entropy? 5. What is the second law of thermodynamics? Does the conversion of energy require the use of energy? 6. Define: a. Catabolism b. Anabolism c. Metabolism d. Exergonic e. Endergonic...