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las n o relationship with the tertiary structure. nuclease proves that the primary structure of a globular the he d) The planes of base pairs using ribo e) Th rs are parallel to the helix axis in the Watson-Crick DNA double helix. e sequence on one strand of n Crick DNA doubld e the helix varies independenty of that in the other strand in the varies in 10. The person n that discovered that A:T and G:C ratios in DNA are approximately 1:1 is discove a) Rosalind Franklin b) James Watson ) Francis Crick d) Ewin Chargaff e) Linus Pauling . Answer eac each). n of the following questions by choosing the right number below (2 pt (1) quaternary (4) primary structure (8) phenyl isothi ary structure (2) central dogma of molecular biology (3) cooperativity (7) Levinthals paradox (5) fluorescamine (6) ATP ocyanate (9 Ramachandran diagram (10) affinity chromatography (a)A type of purification based on the attraction of the protein for a particular chemical grou (b) Detection of amines and peptides (o) States that the flow of genetic information is DNA to RNA to protein. (d) Main carrier of free energy in biochemical systems (e) The native folded state of a protein by a random search among all possible configuration take an enormously long time. Yet proteins can fold in seconds or less. (2) Determination of the amino acid sequence of a small peptide (Edman degradation) (g) Plot of the degrees of rotation about the bond between the a-carbon and the C-O carb in the peptide bond vs the degree of rotation about the bond between a-carbon and the N ato (h) Polypeptide chains can assemble into multi-subunit structures. (i) Linear amino acid sequence G) All-folded or none-folded process in protein folding
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