Does a gene conversion event always lead to a phenotypic change? Explain please
- Does a gene conversion event always lead to a phenotypic change? Explain please
Homework Answers
Gene conversion is a process in which replacement of homologus DNA sequence with other DNA sequence or non reciprocal currection of correction of DNA sequence or gene with other DNA sequence or donor sequence , after conversion both sequence occur similar.
Gene conversion is classified in to two Allelic and Ectopic
Allelic gene conversion is the replacement of allele of one gene with other, which occur during meosis, during meosis homologus recombination of heterozygotic region cause mismatch pairing which leads to the transfer of one of the allels to the other.
Ectopic gene conversion is nonallelic, the replacement one of the paralogous sequence of DNA with other.
Gene conversion leads to human genetic disease,.which always not induce phenotypic change but gene conversion which induce change in genomic DNA which have a significant effect on phenotypic changes which leads to evolutionary changes. Ectopic gene conversion is more effect on genomic DNA and phenotypic change than allelic gene conversion.
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Does a gene conversion event always lead to a phenotypic
change? Explain please
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