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Why do helices make better folding nuclei when compared to beta sheets?

Why do helices make better folding nuclei when compared to beta sheets?

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Answer #1

This is due to the fact that when helices forms hydrogen bonding also tends to takes place within the helix itself and thereby stabilizing it.

Beta sheets are less stable because of energy barrier that arises between folded and non folded state.

Thus due to this reason helices makes better folding nuclei in comparison to that of beta sheets.

Hope this helps you

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