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How can Microbes affect the human response to medicines? What are examples of current research/trials? Disadvantages?

How can Microbes affect the human response to medicines? What are examples of current research/trials? Disadvantages?
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Answer #1

Dear Student ,

* Antibiotics -> They kill infectious bacteria. But they also affect the natural flora. It can result in some worst scenarios like yeast infections, problems related to GIT, etc.

* Chemotherapy drugs -> Some Gut flora modify some drugs during metabolism . This can cause stomach upset .  

Recent approaches :

* DNA based approaches : 16S rRNA, 18 S , ITS gene sequencing.

* RNA based approaches : Metatranscriptomics.

* Metabolite based approaches : Metabolomics.

* Protein based approaches : Metaproteomics.

All the best ??

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