Question

How many cycles of β oxidation are necessary to completely catabolize decanoic acid (CH3(CH2)8COOH)?

Answer 1

Any B. oxidation - Most fatty acids are degraded by the sequential removal of two Carbon fragments from the carboxyl Gran end of a fatty acid. Decanoic acid is locarbon chain so it requires 4 cycle of ß- oxidation for complete oxidation Here we show only one cycle of ß- oxidation of decanoic acid. CH₂ - CH₂ - CH₂ - CH2 - CH₂ - CH₂ - CH₂ - CH₂ - CH₂ - Coon ( Decanoic acid) Co A R-ch-cho-c-oH & o-Carbon talty wid ll Acylco A. R-CH-CH₂-C~s-con - Acylico. A + AMPAPP," oxidation So in one cych of p-oxidation 2 carbon remove as acetyl co A. So it requires e B-oxidation cycle for I complete catabolism of decanoic acid. - R-6=4-(~S-COA H Hydrolysis L. ß Encyl to A OH do R-CH-CH₂-cns-CoA 3-Hydroxy acyl GA I oxidation R-C-CH2-c-S-CA B- ketoacyl coiA Thiolyd- R-C ~S-CoA + CH₂ - (ns.ca fatty aryl co-A . Acetyl coA.