Is fentanyl soluble or insoluble in water and explain why or why not.
Answer:
fentanyl is soluble in water.
Explanation:
Structure of the Fentanyl :

The presence of an amide group act as a source for intermolecular hydrogen bonding with water.
Again the piperidine group enhances the solubility in water. The nitrogen of the N-methyl-piperidine group has a lone pair and can also form a hydrogen bond with water. This acts as a hydrogen bond acceptor.
Hence the molecule fentanyl is soluble in water.
Is fentanyl soluble or insoluble in water and explain why or why not.
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