Question

Write:

trade and generic name

usual dose and frequency

Drug classification

Indications/use

Action/effect (what is expected patient response to MOA)

Main side Affect/Adverse reaction

Nursing intervention ( vitals prior and after, patient teaching) of the following

!)Apixaban 5mg

2) Escitalopram 10mg

3) Miconazole nitrate/ PWD 2%

4) sulfasalazine 500mg

PLEASE TYPE :)

Answer 1

Drugs	Trade and generic name	Usual dose and frequency	Drug classification	indication/use	Action/effect	Main side effect/adverse reaction	Nursing intervention
1.Apixaban 5mg	Trade name Eliquis Generic name Apixaban	Recommended dose is 5mg twice daily In case of DVT first 7 days 10mg twice daily then changed to 5mg twice. In case of NVAF dose changed to 2.5mg twice daily.	Factor Xa inhibitors.	*Used in DVT and pulmonary embolism. *Used in patient with risk of stroke due to embolism.	It is a inhibitor of free and clot bound factor Xa which is a catalyst help to convert prothrombin to thrombin.this thrombin is needed for fibrin clot formation	It increase risk of bleeding. Risk of hematoma formation. Allergic reactions.	Nurse should check the vital signs especially blood pressure and pulse before administration. Teach the patient to inform any bruices or bleeding occur. Instruct patient to inform health care provider if any allergic reaction occur.
2.Escitalopram	Trade name Cipralex Generic name Escitalopram	Adults             In case of depresssion and anxiety disorder recommended dose is 10mg/day.	SSRI(selective seratonin reuptake inhibitor)	Used in treatment of generalized anxiety disorder. Used in treatment of depression. Used in OCD(Obscessive compulsive disorder)	It increases the level of seratonin by blocking the reuptake of neurotransmitters into the presynaptic neuron.	It result in Delayed ejaculation Loss of sexual interest. Increase tendancy to suicide. Weight gain.	Avoid use of alocohol along with this drug. Instruct the patient to continue the dosage because this drug take one weeks for maximum effect. Teach the patient use of this drug avoid during pregancy.
Miconazole nitrate/PWD2%	Trade name Monistat Generic name Miconazole	It used in following dosages 100mg-2% 200mg-2% 1200mg-2%	Antifungal medications	Used in athlet's foot and ring worm infections. Used in angular cheilitis	It inhibit 14 alpha sterol demethylase whch is a fungal enzyme so it cause reduce production of ergosterol found in fungus.	Drug interactions occur when use along with anticoagulants,cyclosporin and atypical antipsychotics.	Instruct patient to take complete course of treatment and avoid contact with eyes. Instruct to inform physician if any allergic reactions or skin irritation occur. Only use dressing over applied area if physician is instructed.
Sulfasalazine 500 mg	Trade name Azulfidine. Generic name Sulfasalazine	Adult dosage for ulcerative colitis 3000-4000mg/day Pediatric dose 40-60 mg/kg. Dosage in rheumatoid arthritis Adult dose 500-1000mg/day.	Gastrointestinal mucous membarine agent.	Used in treatments of Rheumatoid arthritis. Ulcerative colitis. Chrons disease. Psoriatic arthritis	Sulfasalazine metabolized in colon into sulfapyridine and mesalazine this metabolites have anti-inflammatory and antibacterial effects in body.	Common side effects are Infertility,Depression Thrombocytopenia Megaloblastic anemia. Folate deficiency.	Nurse should observe for GI symptoms which may developed few days during treatment and inform physician if any dose adjustment needed. RBC folate level should be measured in case of patients who take high dose of treatment. Inform the patient that colour change (orange or yellow) occur in urine due to this drug. Instruct the patients to avoid breast feeding when taking this medication.