Question

PN 220 Pharmacology Parkinson's Ddisease - Symmatrel & Eldepryl A patient with Parkinson's disease will be starting therapy with amantadine (Symmatrel). He asks the nurse, "How long will I have to take this medication? 1. What would your response be to this patient? 2. What is the purpose of changing medications for the patient diagnosed with Parkinson's disease? The nurse completes an assessment on a patient who is visiting the clinic for a two-month follow-up appointment after starting selegiline (Eldepryl) 10 mg by mouth daily. The patient is pleased with the improvement in is Parkinson's disease symptoms but states, "My wife told me that I cannot eat cheese or drink wine anymore. I hate that. I really do not want to take this medication anymore." 1. Why are these foods restricted when taking selegiline? 2. What is the name of the food product in these foods the patient is to avoid? 3. Name ten (10) additional foods the patient is to avoid.

Answer 1

1.Parkinson's disease is a chronic condition where there is motor or gait functional abnormality due to CNS damages.So the medication has to be taken life long to keep symptoms under control and lead a quality life.

2.The purpose of changing medication in a patient diagnosed with Parkinson's disease are

• To prevent drug interactions
• To reduce the occurence of adverse reactions due to the current drug
• When a patient exhibits levodopa induced dyskinesia ,in order to prevent this the medication can be changed

1.The foods which contains tyramine is restricted here while taking this drug.(cheese,pova,pickled meat,air dried meat,pepperoni, alcohol etc.,)

Taking these foods which are high in tyramine can cause severe allergic reactions.They interact with the CNS when taken and alter its function .They will also increase the blood pressure drastically.

2.Tyramine is the food products which has to be avoided

3.

• Summer sausage
• Tea or coffee
• Cola
• Fermented meat
• Spoiled food
• Overripe fruits
• Soy products
• Marmite
• Red wine
• Corned beef