


Provide the major product(s) for following reactions (4pts each): Cl, H0 1. BH, THE 2. HO,...
1. Provide the missing starting material, reagents, or major organic product for each of the following reactions. (No more than two steps are required in any case where we ask you to fill in reagents.) 1. Mgo, Et20 2. H20 a) Cl b) MgBr OH , Et20 2. H* workup c) OH d) NaOH (cat.) e) OH NaBH4, CeCl3, MeOH
Predict the MAJOR product for the following reactions. (3 pts each) Br2, hv Br2, hv Br2, hv Bry, hv Provide the missing reagents for the following reactions. (Hint:There may be more than 1 step) (4pts each) OH HO
Complete the following reactions. Provide the missing reactant(s) OR major organic product(s). Show correct regio- and stereochemistry for products you draw, where applicable Сн,, Zn(Cu) 1. OSONMO, pyridine 2. NaHSO, H,0 H2O* g. V 1. BH-THF 2. 1,0,, NaOH, HO - Y 1. MCPBA 2.4,00 DCM H,802, H2O heat 1., 2. Zn, AcOH
11. Provide the major organic product in the reaction below. 1. BH, THE 2. HO, HẠO: 12. Provide the major organic product in the reaction below. Hy Lindlar catalyst 13. Provide the structure of the major organic product of the following reaction. H, (excess) Pd/C 14. Which is the correct order of decreasing acidity in the following compounds? H20 CH3CH3NH3 CH2-CH2 HC=CH А в C E A) AME>C>D>B B) A >E>D>B>C CE>A>C>B>D D) A > C>E>D>B E) E>D>B>A>C 15. What...
1. For each of the following reactions, provide the structure of the major organic product(s). Show all the relevent stereochemistry clearly. who CH2OH reflux CH2CH3 Na SET Br DMSO, 20 °C I- A to CH2CH3 CH3 H- EtOH OTS 20 °C Me NaNH2 NH2 DMSO dilute solution of substrate 2. Complete each of the following reaction by providing reagents and conditions (solvent. temperature, concentration, etc.) so that the product shown will be the major one. Note: for c), two steps...
1. Fill in the missing starting material(s), reagent, or major product(s) for the following reactions. NaOH Н. ? heat (Show all major products) RCO3H ? (Show one major product) & dy Hymy NaBH4, H20 HO ? ? HO
Provide the missing reagents for the following reactions. (Hint:There may be more than 1 step) (4pts each) OH HO Continued on next page.
1. (4 pts) Draw the major product(s) for each reaction shown in the following spider diagram. 1) MCPBA 2) H2O 1) BH, in THE 2) H2O2, NaOH 2. (8 pts) Propose a two step synthesis for each of the following transformations. • no n он collowing transformasie Y-X 8-0 oo 3. (8 pts) Fill in the reagents for the reactions shown in the following spider diagram.
Structure Analysis Provide the major product for the following reactions: 1. BH, THF 2. H2O2.NaOH Os04 NMO THF/H20 1. NaNH2 2. H20 HOSO, H2SO4 но 13. For one of the following reaction, provide a complete and detailed electron pushing mechanism accounting for the product that is obtained/indicated. Only one reaction mechanism will be graded. Use proper arrows. HB
Provide a chemical structure(s) for the major product in the structure(s) for the major product in the following reactions. If a chiral center is produced please give the correct stereochemical assignment at the chiral center (Q. 14,3 pts ea.). HBT 1. Peroxides HBr HO NaOH HO Eto Nat Br EtOH 5. Show how to convert cyclohexane into racemic 3-bromocyclohexene. Provide all reagents and structures of molecules synthesized along the way. (8 pts).