Which of the following best represents hydrogen bonding in methanol? CH3-0 H ---CH3 - O CH3- O ----CH3-0 CH3-0 0-CH3 H -----H O CH3- O ----- H-0 он сня
O HN(CH3)2 Cl 12. When 5-hydroxypentanal is heated in methanol with a small amount of an acid catalyst, the following reaction product can be isolated in excellent yield. Write a mechanism for this reaction. (8 pts) HO H CH3OH OCH3
Hot KMnO, OH HO 1. CHECO,H 2. H,O H ,O* ? Cold KMnO, H2O/OH -CH3 MCPBA CH3CH2CH2CH2C= CCH2CH3 Na/CH2CH NH2 Hydrogenation
What is the relationship between the following compounds? O H H HO HO- HOC CH3 CH3 Enantioners Diastereomers Identical molecules Geometrical isomer What is the relationship between the following compounds? HOME HOyC..., COZH COH Enantiomers Diastereomers Identical molecules Geometrical Isomers
CH3 H 1. NaBH/Methanol 2. HO dominant product. Provide your reasons. b) Label ALL optical active carbons. c) List 2 methods to determine whether the reaction is finished (completed);
EXERCISE Writing Reaction Mechanisms: Acyl Transfer Electron pairs :0: H-o-H CH3 C Erase + Na :0– CH3 :0 - H Write the first step of the reaction mechanism using curved arrows to show electron reorganization. 0 O H3C- + Na OH HO + H-ô-CH 0 - Nat OCH < Recheck Next (1 of 5)
CH3 CH3 CH3CH2C=CH2 + CH2OH 12304, CH3CH,Ć-OCHz CH3 Treating 2-methyl-1-butene with methanol in the presence of sulfuric acid gives 2-methoxy-2-methylbutane. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions no XT CH3. HO CH₂ H-ö-CH3
Which of the following depicts a soap molecule? (CH2) 16CH, H2C(H2C)16 (CH2) 16CH Na o (CH2) 16CH3 a b HO (CH2) 16CH Na o CH3 с d Zoom A A B B С с D D X i (CH2)16CH3 H2C(HC)16 (CH2) 16CHE Na o (CH2) 16CH3 a b i HO (CH2) 16CH3 Na o CH3 C d
= CH3 OH Aqueous =O HO- O=O=O CH3 acetone +NH 2. b a + H2NNH2 s NH, C . a = Proton transfer b = Lewis acid/base c= Radical chain substitution d = Electrophilic addition e=E1 Elimination f=E2 Elimination g=Sn1 Nucleophilic substitution h=Sn2 Nucleophilic substitution Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. 1.
g. Ph-C(O)-NH2 4 NaOH Br2 h. (HC)2CH-C(CHa)2 -> HO N(CH3)3 i. Ph-N2, CI- + CuCN --> H30* (cat) Na/ETOH j. cyclohexanone+ H2NOH Pd(OAc)2 (1 mole%) k. Ph-I + 4-O2N-C&H4-HC=CH2 Cul/Pd(PPH3)4) L. HO-CH2-CH2-CC-H +1-CH=CH-(CH2)4-CH3