
Ans
provide the mechanism of the following reductive
amination
NH2 H₂N |—NH HN- ОН Amberlyst 15 Ethanol, NaBHA OH HO Unknown Carbonyl Compound (2 equivalents)
NaOH, Br CH,NH + CO2 H20 H₃C' `NH₂ Amides can be converted into primary amines with the loss of a single carbon atom by the Hofmann rearrangement base Draw curved arrows to show the movement of electrons in this step of the mechanism Arrow.pushing Instructions Br H3C N Submit Answer Try Another Version 1 Hemattempt remaining
27. a. Provide a detailed, stepwise mechanism for the following transformation: i + NH;r cat H + NH2R cat H". b. Provide a detailed, stepwise mechanism for the following reactions: c. Provide a detailed, stepwise mechanism for the following reactions: Oorso.o major minor
H,N. Py H,N. H,N ,C Cl P1 H,N H,N NH H2 NH, H, Compounds A-D are anti-cancer drugs in curren! cⅢical use or under investigation in trials. () Assign oxidation states to all of the platinum ions in molecules A-D (3 marks) () Describe the similar mechanism of action for compounds A-C accounting for any differences. Rationalise the data below in terms of providing effective cancer treatment. Cytotoxicity (CCso in vitro) Maximum tolerated dose 2.3 uM 200 mg m2 51.6...
provide a stepwise mechanism:
10. Provide a STEPWISE Mechanism for the following 40pts a) excess CH3l NH H2CCH2 Ag2O H20, Heat
please draw the mechanism of this reaction
Mes- N N -Mes NaBH4, THF/H20 Mes-NH2 H N—Mes (CH)2 HH 1 week, room temp Mes = 2,4,6-trimethylphenyl
Culion: 10 64. Provide the major organic product(s) and mechanism of the reaction below. 1. LiAIH CILO 2. H20 CH3 Section: 16 65. Provide the major organic product(s) of the reaction below. 1. CH,CH2CH2NH2, H (cat.) 2. NaBH(OAC), Section: 16 66. Provide the major organic product(s) of the reaction below. Ν-Η Section: H* (cat.) 67. Provide the major organic product of the following, CH,CH NH, H (cat.) Section:
Can
you propose the pericyclic reaction mechanism and type of
pericyclic reaction?
1. NH 2. H20
draw the mechanism for all three
Please draw the complete, detailed mechanism for the following reaction. OH H20 HOR OH H.0 -NH₂ H50 | ii | | 反 10min HO* + HOCH2CH3 COCH2CH3 OH
Provide the electron-pushing arrows to complete the mechanism
below. Identify the arrow-pushing pattern(s) used in each step.
(1) Provide electron-pushing arrows to complete the mechanism shown below. Identify the arrow.pushing pattern(s) used at each step. :NH3 H H-NH2 -NH2 NO RO: R R 0 I- -H20 NH2 .NH HN R