
retrosynthetic problem. starting with benzene as the starting product. НО ч.) So, H
How to make 5-hydroxyisophthalic acid, starting with benzene?
он но, о он
Predict the major product of the following reaction:
СНО + K.Сr.0,H,SO, НО
h. and i. Starting with benzene how would you synthesize j.+k. Starting with benzene how would you synthesize I. and m. HAC -NH trace H,00 + H2O CHE o. and p. HẠN H30 NHA KOH/H, - H2O Heat 1) LAH R' 2) H20 H20 Heat t. and u. 1)H,0* HS 2) Raney Ni
4 15. React the following with HNO:/H,SO, and show the final substituted benzene product. On the line provided state if the reaction was Electrophilic aromatic substitution of Nucleophilic aromatic substitution HNO H,SO, HNO,/H,S0 HNOyHSO, HNO HSo HNO,/H,SO NNOyH.SO 0% CH,ONa ?,o ether
2/ Through Retrosynthetic analysis, explain how you would proceed to obtain this product starting from bromocyclohexane:
1/ Through Retrosynthetic analysis, explain how you would proceed to obtain this product starting from bromocyclohexane: og
NaOH H heat о NaBH4, НО НО о RCO3H (Show one major product) ? НО HO
What is the product of this reaction? Starting with benzene, which series of reactions would give the highest yield of this product?
Show the steps required to synthesize the product from the given
starting material.
НО.
8. Design a synthesis of p-nitrotoluene, starting from benzene (3 pts). from to NO2 4 9. Are the following pairs identical, enantiomers, diastereomers, or constitutional isomers? (4 points) (a) Но, Contact and "CH2CH3 H3CH2C" (b) CH2OH CH2OH HO Н HO- -H and CI Н H CI CH3 CH3