ANSWER
3. Dose of patient receiving in mcg/kg/min.
Formula
Dose of patient receiving = Drug concentration * flow rate / patient weight * 60 (min/hr)
Here
Determine drug concentration
800mg in 500 ml = 1.6 ml.
convert to mcg = 1.6 ml * 1000
= 1600 mcg.
Patient weight = 150lbs
1 lbs = 0.45 kg
= 68kg
Flow rate = 30 ml /hr.
As per formula
Dose of patient receiving = 1600 * 30 / 68 * 60
= 48000 / 4080
= 11.8 mcg/kg/min
= 12 mcg/kg/min.
4. Volumetric pump flow rate setting for upper and lower limit
Formula
Flow rate = Dose of patient receiving * patient weight * 60 (ml/hr) / Drug concentration.
Dose of patient receiving at upper limit = 5 mcg/kg/min.
Dose of patient receiving at lower limit = 2.5 mcg/kg/min.
Patient weight = 50 kg.
Drug concentration = 250mg /500 ml
= 0.5 ml
= 0.5 * 1000
= 500 mcg.
As per formula
Lower limit flow rate = 2.5 * 50 *60 / 500
= 7500 / 500
= 15 ml/hr.
Upper limit flow rate = 5 *50*60 / 500
= 15000/500
= 30 ml/hr.
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