Question

Procaine is a popular local anesthetic used in dental procedure and it is an esther linked drug that blocks sodium channels. Why are the effects of this drug temporary? What is another way to practically inhibit the action potential and would the Institutional Review Board (IRB) approve of this technique?

Answer 1

TEMPORARY EFFECT OF THIS DRUG:

TEMPORARY Effeur OF THIS DRUG * allergic Reaction & drowsiness & anxiety & nausea or vomiting

ANOTHER WAY OF INHIBITING ACTION POTENTIAL:

Another way of Practically inhibiting the action potential ~ Ouabin (which is found in the roots, reeds of Acokanthera şchimpeni - gt inhibits action potential by decreasing the enzyme function. Natl. Alpase

INSTITUTIONAL REVIEW BOARD APPROVEL

INSTTUTO NAL REVIEW BOARD APPROVEL : Though ouabin is an toxic subertance In lower doses it can be used as an potent Action potential inhibitor and does not cause any major effects on humans, so the Institutional review board may approve this technique,