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A patient comes into your office presenting with a bacterial infection. You prescribe 500 mg azithromycin...

A patient comes into your office presenting with a bacterial infection. You prescribe 500 mg azithromycin (oral). From what you know about this drug, the peak plasma concentrations range from 0.35-0.45 mg/L. Assuming a plasma concentration of 0.40 mg/L, what is the Vd of this drug?

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Answer #1

ordered dose= 500 mg

peak plasma concentration range=0.35-0.45 mg /L

plasma concentration=0.40 mg/L

Vd=?

Formula: Vd= amount of drug in the body at a particular time / plasma drug concentration at that time

Vd=500mg / 0.40 mg/ L

Vd=1250 L

1250 L is the Vd of azithromycin drug.

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