the nurse is assessing factors that may affect the absorption of a drug that the nurse will soon administer.what factor should the nurse prioritize?
ANSWER.
* Factors affect the absorption of drug includes
1) Lipid solubility
Drugs which are lipid soluble absorb faster than non lipid soluble
drugs.
2) Diseases and disorders
Abnormal health conditions which affect the normal functioning of gastrointestinal
system syndrome results in decreased absorption of drugs.
eg; Malabsorption syndrome.
3) Intestinal motility
High intestinal motility results in lack of adequate time for absorption of a drug.
4) Gastric emptying.
Delayed gastric emptying negatively affect the absorption of a drug.
5) Food.
Some drugs take along with food results in increased time for absorption.
6) pH of drug
Acidic drugs well absorbed in the acidic medium of the stomach.
Basic drugs absorbed in the basic medium of the intestine.
7) Form of a drug.
Drugs in gaseous form absorb faster than solids and liquids.
8) Disintegration of a drug.
If the disintegration of a drug after ingestion is high then absorption rate will be high.
9) Vascular supply.
If the vascular supply to the gastrointestinal system is high then the rate of absorption
will be high.
10) Size of the drug particles.
High molecular size drug particles rate of absorption is low compared to small size
drug particle.
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