Question

Acyl Derivatives rev. 10/27/2019 page 5 Drow the expected products from reaction with organometallics reagents: CEN CHILE CH NH OH ے کردیا ہ والا H₂O + MgBr 'SCH₂ (2 equiv) 7. Hydroxy aldehydes will cyclize to a lactol in a manner that resembles lactone formation: HOH OH Draw the expected lactol from this hydroxy aldehyde:

Answer 1

All are examples for Nucleophilic addition reaction.

6. Nitrile with R-Li/RMgX gives Ketone

Ester with excess Grignard reagent/RLi gives tertiary alcohol

Acid chloride gets converted into ketone by Gilmanns reagent R2CuLi

Lactones gives tertiary alcohol with excess Grignard reagent.

7. Cyclic hemiacetal is formed by Nucleophilic addition

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