15. What is the diffusion coefficient (m/s) in water at 25°C of a bovine pancreas ribonuclease...
The diffusion coefficient, D, of a rigid spherical molecule is given by the equation KT Dua 6 where n is the viscosity of the solvent, r is the radius of the sphere, k is the Boltzman constant 1.38 x 10-6 erg.K-, and T is the absolute temperature in kelvins. Assume that this protein is an unhydrated, rigid sphere with a density, p, of 1.35g.cm . Calculate the diffusion coefficient of a 100 kDa protein in a membrane that has an...
The diffusion coefficient for horse hemoglobin in water is 1.26 × 10–10 m2 s–1 at 40 °C. The viscosity of water at 40 °C is 0.653 × 10–3 kg m–1 s–1. Estimate the radius of hemoglobin assuming the molecule to be spherical and obey Stokes’s law. Comment on the size of Hemoglobin to a corona virus unit which has a diameter of 120 nm.
Suppose that a force of 1 pN is applied to a globular
100 kDa protein. In the absence of damping, how fast will the
protein be moving after 1 ns? During this time, how far will the
protein have moved? GIven the damping coefficient quoted in Table
2.2, what is the actual terminal velocity of the protein?
Table 2.2 Physical properties of a globular protein of molecular mass To0 Property Mass Density Volume Radius Drag coefficient 60 pN-s/m Diffusion coefficient...