Question

8. Provide the reagents necessary to carry out the following conversions. Он NH2 B (a) NH2 Он D А. В. с . (b)

Answer 1

(b) Step C : Friedel Crafts Alkylation followed by Reduction of -NO_​2 by Sn/HCl to NH_{​​​​​2}​.

NH3, N2 (a) El then [reductive] then Na(CN) BH3, THE reductive amination / A CH3 I (excess), then | Ag₂0 and heat. m-CPBA, LCH₂Cl2 (meta-Chloro- per-benzoil-acid) NaN 3, then ppha /H20 Hofmann Eliminatim Exaustive methylation OH NH₂ Conc. H₂SO4 /A CHNO3 and then Naot then H₂O (A) Nar! 02/HU, 0-5°c and then | H₂PO2 Featz, NH2 then Sn/Hu. NO2 OH 1

Step D : Diazonium chloride formation followed by removal of Diazonium, to form the product, by H₃PO_​2.