Question

er CASE STUDY #1 A 25 year old Cambodian refugee in his first trimester of pregnancy developed symptoms consisting of frequent high fever (104 degrees F) accompanied by malaise, headache confusion and nausea in 3 day cycles. Initially, she attributed the symptoms to her pregnancy but later reported them to her physician. Clinical findings included thrombocytopenia tachycardia, splenomegaly, hemoglobinuria and anemia. She was admitted to the hospital and shortly went into a coma 1. The correct presumptive diagnosis would be an infection caused by A. Plasmodium vivax B. Plasmodium ovale C. Toxoplasma gondii D. Plasmodium falciparum E. Pneumocystis species 2. A confirmation of the diagnosis could be made by A. patient history B. A Giemsa-stained thin blood smear C. direct microscopic examination of a fresh blood specimen D. culturing a blood sample in an enriched medium E. an indirect fluorescent antibody test (IFA) 3. Administration of the following drug(s) of choice would normally result in a dramatic cure. A. mefloquine B. chloroquine phosphate C, quinine sulfate, pyrimethamine and sulfadiazine D. quinine dihydrochloride, i.v. E. pyrimethamine, sulfadoxine and chloroquine 4. Organisms resistant to the first-choice treatment are given: A. mefloquine B. quinine sulfate, pyrimethamine and sulfadiazine C. quinine dihydrochloride, i.v. D. chloroquine phosphate E. pyrimethamine, sulfadoxine and chloroquine

Can I have an explanation for each of the answers, how and why it is that answer.
-thankyou

Answer 1

1. The correct presumptive diagnosis would be an infection caused by Plasmodium Falciparum

2. A confirmation of the diagnosis is made by Giemsa Stained thin blood smear

3. Administration of the following drugs of choice Pyrimethamine, Sulfadoxine and Chloroquine would normally result in a dramatic cure

4. Organism resistant to the first-choice treatment are given Chloroquine Phosphate

5. The vector for the transmission of this disease is Mosquitoes

6.The developmental form of the parasite transmitted during the biting process by the Sporozoite

7. Microscopic examination of stained, infected red blood cells would reveal: Spherical gametocytes

Case study #2

1. The history and immune state of the individual are consistent to support further serological tests for :

A. Malaria

2. A Giemsa stained blood smear would most likely show:

E. Circular cysts with flattened sides

3. Infection was most likely acquired through:

B. Ingestion of contaminated foods

4. Drugs of choice used in treating the infection include :

A. Chloroquine

5. Pregnant women should not be exposed to the pathogen because :

B. There is a risk of transplacental infection of fetus