6. The correct option is A.
After positive selection in the cortex, immature T cell lymphocytes then move to the medulla and any cells that recognize high avidity self-antigens presented on MHC (I or II) are killed through APOPTOSIS.
6) A newly-generated T cell can recognize MHCs and is not self-reactive. What is its fate?...
immunology: Indicate what step is correct (Select all that apply) Lymphocytes travel through the body in the lymph as well as the blood Lymphocytes leave the blood through the walls of fine capillaries in 2ry lymphoid organs After spending some time in the LN, lymphocytes leave in the efferent lymph Lymphocytes return to blood at the subclavian vein A lymphocyte after encounter an antigen to which its receptor binds, stops recirculating. The spleen has no connection to the lymphatic system...
1. At the molecular level, what drives B cell development in the bone marrow? 2. What is the role of stromal cells in B cell development in the bone marrow? 3. Describe the sequence of events in B cell development with respect to rearrangement of heavy and light chain Ig genes. 4. Why does Ig gene rearrangement often fail to produce a functional protein product? What mechanisms exist to overcome this problem? 5. What is “allelic exclusion” and what is...
Indicate what step is correct (Select all that apply) Lymphocytes travel through the body in the lymph as well as the blood Lymphocytes leave the blood through the walls of fine capillaries in 2ry lymphoid organs After spending some time in the LN, lymphocytes leave in the efferent lymph Lymphocytes return to blood at the subclavian vein A lymphocyte after encounter an antigen to which its receptor binds, stops recirculating. The spleen has no connection to the lymphatic system Lymphocytes...