Question

. Identify disease conditions in which beta adrenergic blocking agents should not be used and discuss...

. Identify disease conditions in which beta adrenergic blocking agents should not be used and discuss why they should not be used.

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Answer #1

Asthma and chronic obstructive pulmonary disease are the condition in which b blockers should not be used

Explanations

Usually there are 2 type of beta receptors beta 1 and beta 2

Beta 1 is mainly present in heart and kidney while beta 2 are mainly present in bronical smooth muscle ,pregnant utreus skeleton muscle smooth muscle

Non selective beta blocker or beta 2 blocker should be avoided in patient with COPD AND ASTHMA

Cardio selective beta blocker (beta 1 blocker ) produce less effect on lungs and can be used in mild to moderate asthma if required

Why beta 2 blockers should not be used in asthma ?

Beta 2 receptors are present in the bronchial smooth muscles . So when we use beta blockers there is Blockage of beta 2 receptor in bronchial smooth muscle which can produce severe bronchospasm in patient with COPD and asthma

B blockers are also contraindicated in

Myasthenia gravis because they block b2 receptors on skeleton muscles

B blocker also delay the recovery of hypoglycemia so should be closely monitored when given in diabetes

Hope you find this helpful thank you ☺️?

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