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Assume each of the following scenarios occurs in an older adult patient. Describe what the primary...

Assume each of the following scenarios occurs in an older adult patient. Describe what the primary problem is and how it may be avoided or corrected.

A patient started on a new H2 antagonist for a peptic ulcer at normal dosing develops confusion a few days later.

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Answer #1

Central nervous system toxicities mostly develop in elderly, with 2 or 3 week of continuous H2 antagonist therapy

The problem can be corrected by

-immediate withdrawal of the drug for 2 or 3 days.

-administer drug aftet obtaining serum creatinine values.

- famotidine 20mg is recommended and causes less CNS effects

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