Question

Acyclovir 1000 mg IV q.8h. is ordered for the immunosuppressed patient with herpes simplex encephalitis. The pharmacy sends a 1 g vial of acyclovir with the following instructions: Reconstitute 500 mg or 1 g vial with 10 mL or 20 mL, respectively, of Sterile Water for Injection. The resulting solution in each case contains 50 mg acyclovir per mL. Shake the vial well to assure complete dissolution before measuring. The nurse should dilute the powdered medication with ____ mL of sterile water and administer _____ mL to the patient.

20 mL of diluent; administer 20 mL to the patient.

20 mL of diluent; administer 10 mL to the patient.

10 mL of diluent; administer 10 mL to the patient.

10 mL of diluent; administer 1 mL to the patient.

Answer 1

Dose ordered=1000mg, convert it to gm =1gm

Dose at hand=1gm

Quantity=20ml

Dose ordered/Dose at hand×Quantity

1gm/1gm×20ml=20ml

Administer 10ml to the client.

Since 1ml contain 50 mg

50mg×20ml =1000mg

So 20 ml

So Ans is A