Question

We have the following women none of which have ever taken any birth control in their lives. Ann is 55 years of age and started menopause at 53 years of age. She has a normal BMI. She divorced her husband 18 years ago and never remarried. Although she gave birth to 3 daughters, she only raised 2 daughters, Beth and Carla by herself Beth is 18 years of age, she has an ideal body weight and has a normal amount of body fat. She is a triplet and her sisters are Carla and Dawn. Her mother is Ann. Beth and Carla have had no contact with their father and do not know that Dawn exists. Carla is 18 years of age. She suffers from a genetic mutation that makes her aromatase 25% less active than normal. Dawn is 18 years of age. Dawn was raised by her father with her 2 older brothers Steve age 27, and Wesley age 26. Like Beth, she has an ideal body weight and a normal amount of body fat. Erin is 25 years of age, She is obese with a BMI of 33. Frances is a 27 years old and suffers from anorexia nervosa and is very lean. She has an irregular ovulatory cycle and only ovulates about once a year.

Compare and contrast plasma leptin levels between Frances, Erin, Carla and Beth.

Compare and contrast plasma adiponectin levels between Dawn, Erin and Frances. And why Erin will reach menopause prior to Beth?

Answer 1

1. Compare and contrast plasma leptin levels between Frances, Erin, Carla and Beth.

Frances: Low plasma leptin levels as she is lean and has anorexia nervosa

Erin: plasma leptin level in the obese was is significantly higher than lean people

Carla: Aromatase deficiency also affects leptin production, causes decreased leptin levels

Beth: Normal plasma leptin levels, as she is a teenager with normal body weight and the normal amount of body fat.

2. Compare and contrast plasma adiponectin levels between Dawn, Erin and Frances.

Dawn: Normal adiponectin levels as Dawn has normal body weight and the normal amount of body fat

Erin: plasma Adiponectin levels are decreased in obese people

Frances: High adiponectin levels as she is lean and with anorexia nervosa

3. And why Erin will reach menopause prior to Beth?

Erin is obese and has high plasma leptin level and low adiponectin level.

She is 7 years elder than Beth.

The body fat change the leptin and adiponectin levels and estrogen levels in the body