Question

CASE STUDY #2 A family of three on a camping trip went swimming in a fresh water pond while traveling in Maine. Eight days later, the normally healthy 3 year-old daughter developed continuous headaches, fever and increasing lethargy. The physician noted she was unresponsive to painful stimuli. A CSF specimen was negative for bacteria but high in protein level. A CT scan revealed massive encephalitis. Four days after admission to the hospital she died 8. The symptoms and history of the child's illness are consistent with a preliminary diagnosis of meningoencephalitis caused by (a) Babesia microsi (b) Entamoeba histolytica (c) Nacgleria fowleri (d) Acanthamocba (e) Balantidium soli Exposure to the causative agent occurred most likely through (a) contact with domestic pets (b) inhalation of bird feces (c) swallowing and inhaling of contaminated fresh water (d) ingestion of contaminated foods (e) soil contaminated cuts or bruises 9. 10. An effective drug for this disease, if administered early and aggressively, is (a) praziquantel (b) niclosamide (c) amphotericin B (d) quinine (e) metronidazole

Answer 1

8. Option D is correct as preliminary history of meningoencephalitis is caused by acanthamoeba

9. Option C is correct as swalloing and inhaling of contaminated fresh water

10. Option E is correct as metromidazole is used as effective for the meningoencephalitis, if administered early and aggresively

11. Option D is correct as causative agent of meningoencephalitis is known to infect and cause disease in more common in male than female