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1. A 20-year-old female was hospitalized with a suspected case of pneumonia. She also had a...

1. A 20-year-old female was hospitalized with a suspected case of pneumonia. She also had a sore throat and fever. To combat the suspected infection, she was given several different courses of antibiotics. During the morning rounds, the physician noted that edema and an elevated blood pressure.

Dipstick:

Microscopic: WBC 0-3 WBCs/hpf; hyaline 1-2casts/lpf, 1-3 granular casts/lpf, 0-1 hgb casts/lpf, Few squamous epis/hpf

Color Red

Clarity Cloudy

SG 1.028 Casts:

pH 6.0

Protein 2+

Glucose Negative

Ketones Negative

Bilirubin Negative

Blood 2+

Urobilinogen Normal

Nitrite Negative

Leukocyte Negative

Other results: 24 hour urine output – 400 mL; 24 hour urine total protein – 1g/24 hours; BUN – 28 mg/dL, Creatinine – 1.6 mg/dL; positive ASO titer

a.what are the abnormal findings present?

b.what is the suspected diagnosis?

c.what is the probable cause?

d. are the bun and creatinin results consistent with the dignosis? why or why not?

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Answer #1

A. Abnormal findings are :-

Urine output 400ml /24hr

BUN -28mg/ dL

Creatinine - 1.6mg/ dL

Total protein 1gm/24hour

B. Suspected of Acute kidney injury

C. Probable cause is the use of several high dose antibiotics

D. BUN and creatinine are raised due to injury to the kidney as they cannot flush out the waste . Hence creatinine and BUN raised .

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