Question

Question 41 In the following synthesis of a potet ant-cancer nazural product, lsiodiplośn, which of che folliuing organomecalic reactons are ubliced? 3 Org,. Chem. 2000, 65, 7990) Select all that apply. Ar CH20 o LICI, NEt DUF CH Ch OT1 Ha Suzuki Coupin9 ta stile Coupling Negish. Couping D Type here to search

Answer 1

Solution :-

Correct options are 4) Heck reaction and 6) Ring closing metathesis

In first step ethylene is used not any stannane hence it is heck reaction not stille coupling though this reaction can be done via stille coupling using any vinylstannane.

Next step is ring clossing metathesis using modified Grubbs catalyst.the catalyst used is not a standered Grubbs catalyst.