
Propose TWO (2) possible pairs of starting materials for the synthesis of the following FDA -approved...
12. Propose a reasonable synthesis for the following molecule. You must use the given starting materials and any reagents we have studied in our course. There are several possible approaches. (30 pts) Br Given: NaCN CH4 CO2
10. Bonus: Propose a reasonable synthesis for one of the starting material product pairs using any additional reagents you may require. Br - Br-> dat duon s- OH
Give a reasonable synthesis for
each of the following compounds from the indicated starting
materials. You may use any other organic or inorganic reagents you
wish unless otherwise indicated. The desired product for each
reaction you propose must be the one of the predominant products.
Give the reactants, conditions (where appropriate) and products of
each synthetic step. If equal mixtures are anticipated (i.e. ortho
/ para products) then indicate where separations are needed. NO
MECHANISMS! [6 points
2. Give a...
the most efficient synthesis possible 6. Synthesis propose to make the compound shown below Starting from benzene. Be sure to include appropriate reaction conditions and products for each step. Steps HO NHL
Provide a reasonable synthesis
Question (2)- Propose a reasonable synthesis of 9 starting from 7 and 8 using any other reagents you might require. (15 pts) OH 7 он
Propose a set of reagents (and steps) for syntehsizing the
following molecules from their starting materials. You may use any
reagants, solvents, and conditions you deem necessary. Place your
answers above and below the reaction arrow.
Please provide explanation and any concepts to study regarding
the topic.
Problem #3 Propose a set of reagents (and steps) for synthesizing the following molecules from their starting materials. You may use any reagents, solvents, and conditions you deem necessary. Place your answers above...
two possible starting materials
using a williamson ether synthesis method.Please explain
two possible starting materials using a williamson ether synthesis method.Please explain
[References] Propose a synthesis of the compound below. Use one of the two starting materials and any of the reagents in the table. CH3 Starting materials 1. CH3C(O)CH2COEt 2. CH2(CO2Et)2 Reagents available a. CH3 Br PY BI h. H30+ heat BVB i. NaOC2H5 /C2H5OH
21. Do Only One! Propose a multistep synthesis using the starting materials shown and any other reagents/reactants you need. To maximize partial credit, be sure to draw out the products of each reaction you propose. You do not need to draw mechanisms for full credit. (7 points) o by OR ОMe
5 (20 pts) (a) Propose a reasonable synthesis, using indicated diketone as starting material. ri and any C4 or less starting materials (SMS) (any reagents are allowed) Hint: as a C3 SM use (6) Propose two syntheses, which will use two distinct methods for construction of the 6-membered ring (1) Crossed-Claisen condensation and (2) Claisen condensation(s). 0 0 selor must use this reagent plus any acyclic Cg or less