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13. Which of the following is a good solvent for S2 processes in general? a) b) c) d) All of these are poor for Sn2. OH
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Answer #1

Answer:-

option a): "2-butanone" is correct answer.

2-butanone

Explanation:-

SN2 reactions are generally favoured by polar aprotic solvents like acetone, DMSO (dimethyl sulphoxide), 2-butanone, DMF (dimethyl formamide),etc. Aprotic solvents cannot form hydrogen bonds, thus , they don't solvate nucleophiles (anions) involved in SN2 reactions. Anions are highly solvated by protic solvents through hydrogen bonding. As a result, reaction rate for SN2 reactions are very fast with anionic nucleophiles in aprotic solvents.

Also, aprotic solvents stabilize the transition state for SN2 reactions.

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