Question

Draw the product of the given reaction sequence. Select Draw =O4 NaOCH3, CH3OH

Answer 1

It is based on the concept of the Reaction mechanism. It can be done as follows:

Given reaction is :- s NaOCH3 си 20 и ( product) This reaction two а a is combination o reaction they are: (a) Michael Addition name

(b) Aldol can be condensation. Mechanism follows: given ad 15+ occurs with Mechanism : In the Step Acid-base reaction substrate and NOOCH3, which attacks the a, Brunsaturated Ketones. Then, due to presence of alphaa hydrogen the aldol reaction which eliminates water molecule heating is done.. occurs e. a at + Naợch3 + CH₃OH co OCH3 (endlate ) attacks at x, ßrunsaturated ketone This enolate 1,4- addition manner. in

Son & Ho M CH₃OH E

R CH3 0: Сн, NaUCH, сH2 Сид 1 Но. СН3- < JOCH т ci OCH3

Elch mechanism. Ö How EICH (Mechanism) (product) Hoon The last Step in volved Thus product formed is; 2 (product) Ans
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Answer 2

Pooe NaQ CH3 Chola NaOch alt take en because its stablised resonance as base and as it in audie conjugate ion in by automerism or Then anion 2,ß- unsaturation 1,4 michael will attack Redone and addition at giver show