Question

QUESTION 9 Using the list, propose the forward synthesis of the retrosynthesis shown below (and number of steps can be used, so long as they get to the desired product in as high a regioselectivity as possible). Please report your answer by typing the letters/symbols sequentially. A. Ph3PMeBr, KotBu, PhMe, 25 °C B. CuBr, 0 °C C. Cu20, Cu(NO3)2, H20, 0 °C D. CuCN, 0 °C E. SO3, H2SO4, 100 °C F. Cl2, FeCl3, THF, 65 °C G. Br2, FeBr3, THF, 65 °C H. ACCI, AICI3, THF, 65 °C 1. H2, Pd/C, EtOH, 25 °C J. KMnO4, H20, 100 °C K. CrO3, H2SO4, Acetone, 0 °C L. NaOH, H2O, 160 °C M. H20, Dilute H2SO4, 100°C N. HNO3, H2SO4, 60 °C O. K2CO3, Mel, MeCN, 82 °C P. mCPBA, DCM, 25 °C Q. KCN, MeCN, 50 °C R. H2NBn, 150 °C S. SOCl2, 75 °C T. LiAIH4, THF, 0 °C U. PBr3, 50 °C V. NaBH4, EtOH, 25 °C W. NaOH, MeOH, 100 °C X. H2SO4, H20, 100°C Y. HBr, EtOH, 50 °C Z. NaNO2, H2SO4, 0 °C !. H2NBn, Et3N, DCM, 40 °C #. Mg, cat. 12, Et20, 35 °C $. MeOH, 25 °C %. NaOH, MeOH, 65 °C ^. CO2, Et20, 25 °C &. HCI, MeOH, 65 °C *. KotBu, HOtBu, 50 °C

Answer 1

Answer:

The reagents for forward synthesis of styrene from benzene is

1. H. AcCl, AlCl₃, THF, 65^oC

2. V. NaBH₄, EtOH, 25^oC

3. X. H₂SO₄, H₂O, 100^oC

Step-I- OH ОН, ht -H H Hason 100°C +H2O Tazget molecule styrene