Question

At least 400 words. Our system will use turn it in to check the work, so please make sure to use your own words.

Please do not use handwriting, I always have trouble to read the handwriting

Children with DiGeorge Syndrome are born without a thymus. Discuss, in detail, the repercussions to body defense mechanisms caused by this disease.

Answer 1

DiGeorge syndrome is also known as 22q11.2 deletion syndrome. This disorder is caused when a small part of chromosome 22 is missing. Basically it is a chromosomal disorder that results in Poor development of several bodily systems.

It can cause multiple problems:-

• Heart defects
• Poor immune system function
• Cleft palate
• Hypocalcemia
• Delayed growth
• Breathing problem
• Learning delays
• Behavior problem s
• Poor muscle tone

Repercussion to body defence mechanism caused by the George disorder are the following:-

• It can cause heart defects that could result in an insufficient supply of oxygen rich blood .for example ventricular septal defect ,TOF.
• Due to to the the deletion of 22 chromosome parathyroid glands are smaller then the normal one so it secrete less parathyroid hormone which leading to hypoparathyroidism.
• in this disorder the thymus gland may be small or missing resulting in poor immune function and frequent severe infection.
• Having problems with the development and function of the brain resulting in learning social development or behavioral problems.
• Many more complications are also seen in this syndrome such as hearing impairment ,poor vision b,problems poor , kidney function etc.