
7) Propose reactions to achieve the following transformations. ОMe "pro-a- d a — Cool d) CHO...
Pericyclic Reactions 1. Predict the products of the following reactions and propose a mechanism that explains it Me a heat OMCN heat 9. Ome =-COME HOY Y hest MeOC 2. Propose a synthesis of the following molecules using acetaldehyde as your only starting material 3. Propose a mechanism for the following transformations Meo,
5. Propose reasonable mechanisms to the following reactions: (5%) CHO CHO 1. OH CHO 2. HO, A co
Propose an efficient synthesis for each of the following
transformations:
12 Propose an efficient synthosis for oach of the following trans- formations Meo OMe Br Br (b)
Propose synthetic routes (a series of reactions; not a mechanism) for the following transformations. Transformation (a) can be done in 2 steps. Transformation (b) can be done in 4 steps.
1. Provide the missing starting materials, reagents, or products in each of the following reactions. H+ OH CH,OH NaOH Meo NH2 room temp. HO OH Meo Me ОН Meo 2. Provide appropriate conditions to convert each of the following starting mana hexanoic acid (some transformations may require more than one step): It each of the following starting materials into OH OH ОMe "NH₂
Part II. Mechanisms!!! Propose mechanisms using arrow-pushing
notations to show the transformations of
the following reactions.
d) CH OH heat CH, OH heel NE он EN E CH OH heat
c and d
3. Propose an efficient synthesis for each of the following transformations: Howy
Problem 23 (cont.) Propose an efficient synthesis for the following transformations. OH c) d)
8. Alcohols are readily available synthetic starting materials. Propose a series of reactions to achieve the following syntheses starting from alcohols. Clearly show the reagents used for each step and the synthetic intermediates. a. For this synthesis, use the given starting alcohols and any inorganic reagents needed. You may use the two alcohols in separate reactions as needed. M OH + OH ... i
Propose synthetic strategies of the following reactions. Provide all the reagents & intermediates needed. Show mechanism for all transformations Major Product?