Question

please calculate the mean and standard deviation for each cohort 4.23 Melanoma treatment. A study by Morgan and coworkers used genetically modi. fied white blood cells to treat patients with melanoma who had not responded to standard treatments. In patients in whom the cells were cultured ex vivo for an extended period of time (cohort 1), the cell doubling times were [8.7. 11.9. 10.0) days. In a second group of patients in whom the cells were cultured for a shorter period of time (cohort 2), the cell doubling times were (1.4, 1.0, 1.3. 1.0, 1.3, 2.0, 0.6, 0.8, 0.7, 0.9, 1.9) days. In a third group of patients (cohort 3). actively dividing cells were generated by performing a second rapid expansion via active cell transfer. Cell doubling times for cohort 3 were {0.9, 3.3, 1.2, 1.1) days. Data are available in Excel and SPSS formats on the companion website as file MORGAN 2006... Create side-by-side boxplots of these data. In addition, calculate the mean and standard deviations within each group. Comment on your findings.

Answer 1

We use following formula to compute mean and sd for each data. ī=Lillisd- 2=(1; – 7)2 en V n-1 We get cohort 1: mean = 10.2; sd = 1.61; We get cohort 2: mean = 1.17; sd = 0.46; We get cohort 3: mean = 1.625; sd = 1.12;