Question

8. (i) Propose a product for the following reaction below and give a mechanism for its formation: 2. K 2HN (ii) Provide a muti-step mechanism for the following reaction: 0 0 CI OCH (ii) The product morpholine is synthesised as shown. Give a mechanism for each of the steps: NHt +
0 0
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Answer #1

first reaction is tosylate intermediate formation and nucleophilic attack leads to formation of product

second reaction is nucleophilic attack and rearrangement leads to the product

third reaction also same nucleophilic attack I.e nh3 attacks on ethylene oxide and forms the rearranged product the mechanism as shown below

CH OH 2 Cts NL :O CHz0 3 NM 0 (G

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