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write equations for the rapid reaction (reaction 1) and the slower reaction (reaction 2) that occurs...

write equations for the rapid reaction (reaction 1) and the slower reaction (reaction 2) that occurs when an aspirin (an acid) reacts in sodium hydroxide (a base) solution

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Answer #1

Shown below a possible mechanism for the reaction of aspirin an acid with sodium hydroxide a base. First step is base picks up the acidic hydrogen off of carboxylic acid to form carboxylate anion. The anion intramoleculary attacks on the acetyl carbonyl carbon which cleaves to form an anhydride type of intermediate. Final step of hydrolytic workup yields the salicylate as the product of the reaction.

slow fast O neutralizatio hydrolysis CH3CO2H

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