Question

Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents. Draw the Grignard reagent and any other organic reagents needed.

11 RUVIUWI Constans i Pendulu Part F Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents. Draw the Grignard reagent and any other organic reagents needed. ОН -C-CH CH, from C-OCH.CH Draw the molecules on the canvas by choosing buttons from the Tools (for bonds and charges), Atoms, and Templates toolbars. O o .. . H: 1200 0 + 1'33 Marvin JS

Answer 1

Ester reacts with 2 moles of Grignard reagent followed by hydrolysis gives 3° alcohol. +MgBr CH3 Olacu Coments abonn - Olan |H,Meer CH3MgBr H3O+ + C-CH3 CHZ MgBrt -C-CH3 CH Part-C 1-cyclohexylethanol is MgBr cyclohexylmagnesium bromide acetaldehyde ether a. ү – а то H20+ MgBr O MgBr+ OH

Part-E formaldehyde H-C-H 9 MgBrHot Mg Ph-Br. ether OH Ph-c-H → Ph-MgBr Ph-c-H. benzyl alcohol Part-E Retro-Synthesis : OH MgBr 2-cyclohexyl ethanol ana Chmis=Q..s a la de la sanoma no ano Synthesis : Mg H20+ Br ether MgBr O MgBr+ OH 2-cyclohexylethanol