Question

Lipolysis:

A. is stimulated by insulin.

B. is inhibited by glucagon.

C. requires the action of hormone-sensitive lipase.

D. requires an apolipoprotein.

E. results in an increase in blood concentrations of esterified fatty acids.

Which one of the following compounds is a COMMON intermediate in the beta-oxidation of fatty acids, ketogenesis and cholesterogenesis?

A. mevalonic acid

B. acetoacetic acid

C. acetoacetyl-CoA

D. beta-hydroxy-beta-methylglutaryl-CoA

E. malonyl-CoA   

If the fatty acid 9-18:1 undergoes two successive chain elongations, the resulting product is:

A. 13-22:1

B. 13-20:1

C. 9-20:1

D. 5-22:1

E. 15-22:1

Answer 1

(A) In lipolysis usually lipids are detached from the carrier of lipoproteins by the right activity of lipoprotein Lipase.

The option 3rd is correct one.

(B) The common intermediate in these three Beta oxidation of fatty acid, ketogenesis, cholesterogenesis are beta- hydroxy beta- methylglutaryl- CoA (HMG-CoA).

During the reaction this intermediate is formed in between all these three , which is cleaved to free acetoacetate and acetyl- CoA .

Therefore, the correct option is D

(C) Questions should have more information for proper answering.