Question

1a.Explain in details the difference between differential display proteomics and shotgun proteomics analysis with examples and diagrams.

1b.Give four advantages and four disadvantages of each method.

Answer 1

short gun proteomics

Identification and quantification of single proteins

.Identification and quantification of proteins in a complex

.Identification and quantification of post-translational modifications.

Protein-protein interaction .

Proteomics :-

Proteomics is the study of proteins at a large scale. The word proteome use in proteomics is a portmanteau of protein and genome.

proteomics as a field that would employ bioinformatic methods to better understand protein structures, development, roles, etc.