In homology modeling, what amino acid would you substitute threonine for if you want to test...
In homology modeling, what amino acid would you substitute threonine for if you want to test if threonine is required for catalytic activity in a protein?
Homework Answers
Threonine can be replaced by serine (amino acid) for catalytic activity because both of them have nearly same hydropathy index.
Reason to support: Protein folding is governed by hydropathy
index of amino acid , higher the hydropathy index more it is
possible that the amino acid will reside interior of the protein
and vice versa in case of hydrophilic amino acid. So a hydrophobic
amino acid can only be replaced by hydrophobic amino
acid.
Also, threonine is hydrophilic so it can be replaced by serine
which is also a hydrophilic amino acid for the catalytic
activity.
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In homology modeling, what amino acid would you substitute
threonine for if you want to test...
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fill in the blanks
the words are
1- unfolding
primary amino acid sequence
regained
hydrogen
disulfide bond
inactivity
instructions
non covlent
lost
refolded
secondy structure
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