Question

PLEASE EXPLAIN THE NEWMAN PROJECTION !!! HOW

Compounds 1 and 2 exhibit an oxetane ring (a four-membered ring containing an oxygen atom), which is a very important structural feature in a number of natural products. For example, an oxetane ring is present in the structure of taxol, used in the treatment of breast cancer. When either 1 or 2 is treated with TsCI and pyridine, followed by t-BuOK, the Zaitsev elimination product dominates, despite the use of a satirically hindered base (Tetrahedron Lett. 2007, 48, 8353-8355). Determine the stereochemical outcome for each of these processes and draw the expected product in each case. Use Newman projections to justify your answers.

Answer 1

I try to draw it in the best way. the dot, mean that is the continuation of the structure. I drew two products, one with the zaitsev elimination and another one with the hydrolisis in the other atom of oxygen to do a zaitzet elimination in other way. there are other elimination products, but I only drew two of them. Any doubt feel free to tell me in a comment.