Question

I. ( ) There are several major characteristics of the generic host response to biomaterials. Which of the following is not one of them? (A) neutrophil activation, (B) macrophage activation, foreign body giant cell production, granulation tissue formation, (C) innervation and muscular activities, (D) fibroblast behavior and fibrosis, (E) platelet adhesion, activation, aggregation 2. The biocompatibility of a device depends on several factors. Which of the following is not one of them? (A) the types of patient tissue that will be exposed to the device, (B) the therapeutical functionality of the device, (C) the chemical and physical nature of the component materials of the device, (D) the duration of the tissue exposure to the device, (E) none of the above 3. ) A temporary fixation device for treating fractured bones has a metal support that is screwed into the bones. It is intended to be used for a duration less than 30 days. Which of the following biocompatibility tests is not likely required under the ISO 10993 guideline? (A) cytotoxicity, (B) subacute and subchronic toxicity, (C) hemocompatibility, (D) genotoxicity, (E) none of the above 4. Biocompatibility tests are almost always required for devices that have significant tissue contact. Supporting dáta can be submitted to reduce the amount of required compatibility tests Which one of the following is not a likely source for supporting data? (A) data from previous submissions for device approval, (B) testing data from suppliers of materials or components (C) analytical data from manufacturers of materials in use, (D) clinical data from the same device or similar devices, (E) data from published scienti fic literature

Answer 1

Ans 1 : C) innervation and muscular activities

The host responds to different biomaterials that are introduced into the body. These responses can be varied depending on the type of biomaterial used and the harm it creates in the body. The innervation and muscular activities are not teh kind of host responses. Rest all other options are correct host responses that body gives against the non compatible biomaterials.