Question

UML Organic Chemistry IA vi) One the same axes, provide a fully labeled energy diagram for the substitution reaction of (R)- and then in methanol (MeOH). Be sure to clearly indicate any difference in the rate between both 65 CHEM.2210 methyloctane with -SH if the reaction were carried out in dimethylsulfoxide (DMSO) reactions, if one is predicted and assume a spontaneous reaction DMSO MoOH Bimolecular substitution reactions are known to work best with primary substrates, strong nucl and good leaving groups. eophi and lahel the following i IUPAC name of subst

Answer 1

vi) Drawn below is the energy diagram for Sn2 reaction in polar aprotic solvent DMSO and polar protic solvent MeOH

The activation energy (Ea) is greatre when reaction is performed in MeOH and thus the reaction is slower than in DMSO.

substitution reaction NaSH Br SH in MeOH solvent in DMSO solvent Ea reactants dHrxn! product reaction coordinate